Engineering precision genetic therapies

What if gene delivery did not require an external carrier?

Using computational design, our novel targeting gene carriers are constructed with single-stranded DNA that folds around its main cargo, the therapeutic single-stranded DNA it is delivering to target cells. These non-viral, non-LNP carriers are non-toxic, non-immunogenic, and non-inflammatory. They can be constructed to encode for virtually any gene of interest and for precise in vivo tissue and cell targeting. Importantly, using proprietary process innovations, we can manufacture the gene carriers in a scalable fashion.

Our novel gene carrier unlocks an entirely new approach to in vivo gene delivery, overcoming critical limitation of existing viral and non-viral gene delivery technologies such as immunogenicity, inflammation and reactogenicity, poor targetability, and tedious manufacturing which have held back the genetic medicines field from bringing critical therapies to patients.